![]() ![]() His mental status returned to baseline following administration of intravenous dextrose and 100 mg of octreotide, a drug that inhibits insulin release and is used as an antidote for recurrent hypoglycemia associated with sulfonylurea toxicity. After 12 hours of confusion, he was evaluated in a hospital emergency department, where a basic metabolic panel revealed a blood glucose of 48 mg/dL (normal = 70–100 mg/dL). His symptoms initially resolved after eating lunch but returned later in the day, and he became increasingly agitated. On August 13, 2019, VPC was consulted by an emergency physician at an academic medical center about a man aged 57 years who did not have diabetes and was noted by his wife to have been diaphoretic and agitated the previous day. ![]() The presence of V8 in the market poses a serious threat to public health because of its potentially life-threatening adverse effects. The public health implications of V8 use include the potential for substantial morbidity from hypoglycemic episodes and the potential for mortality if health care services are not accessed in a timely manner when hypoglycemia occurs. To stem this outbreak, V8 was removed from stores when found, and public service announcements were released. Analysis of the V8 tablets revealed that most contained glyburide, a sulfonylurea oral hypoglycemic used in the treatment of diabetes and associated with prolonged hypoglycemia following overdose ( 1). Over the following 3 months, the Virginia Department of Agriculture and Consumer Services (VDACS) and the Virginia Department of Health (VDH) conducted an investigation and identified 17 patients meeting the case definition (severe hypoglycemia within 48 hours of consuming an over-the-counter male enhancement supplement in a man with no history of use of insulin or other medication used to control blood glucose). In August 2019, the Virginia Poison Center (VPC) and the Blue Ridge Poison Center (BRPC) were contacted concerning patients experiencing repeated episodes of marked hypoglycemia following ingestion of a male enhancement supplement tablet marketed as “V8” in convenience stores in central Virginia. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |